منابع مشابه
Inherited Colon Cancer Syndromes
MEREDITH C. ROATH, MD JACK A. DI PALMA, MD University of South Alabama T he modern age of genetics began in the mid-19th century, and many scientific discoveries led to the sequencing of the human genome. Recent research has uncovered the genetic basis of many diseases, and continued study is certain to lead to more discoveries. The results of this research will continue to change medicine. Gen...
متن کاملInherited cancer susceptibility syndromes in paediatric practice.
Over the last decade there have been rapid advances in our knowledge about the molecular basis of many inherited disorders. Molecular testing is now available for many conditions and may assist in the management of the individual and their extended family. One area where the use of genetic testing has expanded rapidly is in the area of hereditary cancer, particularly in relation to hereditary b...
متن کاملColorectal polyposis and inherited colorectal cancer syndromes
The majority of colorectal cancer (CRC) cases are sporadic, with hereditary factors contributing to approximately 35% of CRC cases. Less than 5% of CRC is associated with a known genetic syndrome. Although adenomatous polyposis syndromes, hamartomatous polyposis syndromes, and those previously classified as non-polyposis CRC syndromes are quite rare, it is important for clinicians to know the c...
متن کاملLeading article Inherited predisposition to pancreatic cancer
Pancreatic cancer is the fifth leading cause of death from cancer in men and women in Europe and North America. The prognosis has not changed significantly despite improvements in diagnosis and perioperative management. Traditional chemotherapy and radiotherapy regimens have been rather ineVective in providing control of the disease. The only consistent risk factor identified so far is smoking ...
متن کاملLeading article Inherited predisposition to pancreatic cancer
Pancreatic cancer is the fifth leading cause of death from cancer in men and women in Europe and North America. The prognosis has not changed significantly despite improvements in diagnosis and perioperative management. Traditional chemotherapy and radiotherapy regimens have been rather ineVective in providing control of the disease. The only consistent risk factor identified so far is smoking ...
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ژورنال
عنوان ژورنال: The Cancer Journal
سال: 2012
ISSN: 1528-9117
DOI: 10.1097/ppo.0b013e318278c4a6